Linking a polyketide synthase gene cluster to 6-pentyl-alpha-pyrone, a Trichoderma metabolite with diverse bioactivities

Linking a polyketide synthase gene cluster to 6-pentyl-alpha-pyrone, a Trichoderma metabolite with diverse bioactivities

Abstract Background Members of the fungal genus Trichoderma are well-known for their mycoparasitic and plant protecting activities, rendering them important biocontrol agents. One of the most significant specialized metabolites (SMs) produced by various Trichoderma species is the unsaturated lactone...

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Main Authors: Daniel Flatschacher, Alexander Eschlböck, Siebe Pierson, Ulrike Schreiner, Valentina Stock, Arne Schiller, David Ruso, Maria Doppler, Veronika Ruzsanyi, Mario Gründlinger, Christoph Büschl, Rainer Schuhmacher, Susanne Zeilinger
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Microbial Cell Factories
Subjects:
Trichoderma atroviride
6-pentyl-alpha-pyrone
Polyketide synthase
Biocontrol
Biosynthetic gene cluster
Specialized metabolites
Online Access:https://doi.org/10.1186/s12934-025-02718-9
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https://doi.org/10.1186/s12934-025-02718-9

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