Toxicity of nuclear-localized GFP in reporter mice

Abstract Various techniques using fluorescent reporter probes have been developed, such as GFP transgenic mouse lines that are used to detect spatial–temporal expression levels of genes. Although GFP expression is largely considered non-toxic, recent reports have indicated that under certain conditi...

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Bibliographic Details
Main Authors: Sudhir Verma, Isabel Y. Moreno, Tarsis F. Gesteira, Vivien J. Coulson-Thomas
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-75741-2
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