Drug-free hyaluronic acid-microneedle with unexpected inhibition activity on benzalkonium chloride-induced corneal inflammation and stromal scarring

Drug-free hyaluronic acid-microneedle with unexpected inhibition activity on benzalkonium chloride-induced corneal inflammation and stromal scarring

Topical instilling of commercial artificial tears (cAT, containing 0.1 % hyaluronic acid) is widely employed to alleviate clinical manifestations of mild dry eye disease (DED) by preventing the pathological change of corneal epithelium. However, it showed limited therapy effectiveness on heavy DED w...

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Bibliographic Details
Main Authors: Baoshan Huang, Rui Zeng, Xiao Liu, Lu Pan, Haitong Bai, Jiachen Liao, Wenkai Xu, Hong Fu, Kaihui Nan, Sen Lin
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Microneedle
Hyaluronic acid
Artificial tear
Dry eye disease
Corneal stromal scarring
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425002819
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http://www.sciencedirect.com/science/article/pii/S2590006425002819

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