Intrinsic Alu affects for RNA splicing in a minigene model

Alu elements are commonly located in the introns of primate genomes and, once transcribed, can alter splicing patterns. The insertion of an antisense Alu element into intron 9 was shown to enhance exon 10 skipping in a previously developed ACAT1 minigene model including exon 9–exon 11. This study in...

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Bibliographic Details
Main Authors: Mina Nakama, Bunta Imanaka, Yuma Kimoto
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biochemistry and Biophysics Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405580825000895
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