Where antibiotic resistance mutations meet quorum-sensing

Where antibiotic resistance mutations meet quorum-sensing

We do not need to rehearse the grim story of the global rise of antibiotic resistant microbes. But what if it were possible to control the rate with which antibiotic resistance evolves by de novo mutation? It seems that some bacteria may already do exactly that: they modify the rate at which they mu...

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Bibliographic Details
Main Authors: Rok Krašovec, Roman V. Belavkin, John A.D. Aston, Alastair Channon, Elizabeth Aston, Bharat M. Rash, Manikandan Kadirvel, Sarah Forbes, Christopher G. Knight
Format: Article
Language:English
Published: Shared Science Publishers OG 2014-06-01
Series:Microbial Cell
Subjects:
evolution
mutagenesis
fluctuation test
autoinducer 2
autoinducer 3
stress-induced mutagenesis
DNA methylation
optimal control
Online Access:http://microbialcell.com/researcharticles/where-antibiotic-resistance-mutations-meet-quorum-sensing/
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