Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel‐Like Structures in Hydrogels for Tissue Engineering

Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel‐Like Structures in Hydrogels for Tissue Engineering

Background Organs and tissues need to be vascularized during development. Similarly, vascularization is required to engineer thick tissues. How vessels are formed during organogenesis is not fully understood, and vascularization of engineered tissues remains a significant challenge. Methods and Resu...

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Main Authors: Chinmoy Patra, Amey Rayrikar, Ganesh Wagh, Florian Kleefeldt, Kaveh Roshanbinfar, Florian Cop, Iva Nikolic, Mirko H. H. Schmidt, Amparo Acker‐Palmer, Süleyman Ergün, Felix B. Engel
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
extracellular matrix
nephronectin
tissue engineering
vascularization
zebrafish
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.037943
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https://www.ahajournals.org/doi/10.1161/JAHA.123.037943

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