Personalized colorectal cancer risk assessment through explainable AI and Gut microbiome profiling

Personalized colorectal cancer risk assessment through explainable AI and Gut microbiome profiling

The clinical adenoma – carcinoma progression represents a well-established framework for understanding colorectal cancer (CRC) development, although the molecular mechanisms underlying this transition remain only partially understood. Increasing evidence suggests the gut microbiome (GM) as a key mod...

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Bibliographic Details
Main Authors: Pierfrancesco Novielli, Simone Baldi, Donato Romano, Michele Magarelli, Domenico Diacono, Pierpaolo Di Bitonto, Giulia Nannini, Leandro Di Gloria, Roberto Bellotti, Amedeo Amedei, Sabina Tangaro
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Explainable AI
microbiome
colorectal cancer
biomarker
SHAP interaction analysis
risk stratification
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2543124
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2543124

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