Osteopontin protects from ovalbumin-induced asthma by preserving the microbiome and the intestinal barrier function

ABSTRACT The gut and lung microbiota are associated with asthma. Osteopontin (OPN) is an important cytokine associated with several inflammatory diseases. The potential role of OPN in the asthma-associated microbiome remains poorly understood. Here, we investigated whether OPN could moderate asthma...

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Bibliographic Details
Main Authors: Jinli Huang, Hongyu Qiao, Qiuhong Li, Yi Zhang, Chenyu Zhang, Hui Su, Xin Sun
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msystems.00389-25
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