Emerging role of SETD2 in the development and function of immune cells

SET domain-containing 2 (SETD2) is a methyltransferase that catalyzes trimethylation of lysine 36 on H3 (H3K36me3) in mammals, an epigenetic mark associated with actively transcribed regions. SETD2 is implicated in multiple chromatin biological processes, such as alternative splicing, transcriptiona...

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Bibliographic Details
Main Authors: Longmin Chen, Yuan Zou, Yan Dong, Tian Hong, Qianqian Xu, Jing Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-11-01
Series:Genes and Diseases
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352304225001114
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