Effectiveness of dupilumab treatment against refractory eosinophilic chronic rhinosinusitis

Effectiveness of dupilumab treatment against refractory eosinophilic chronic rhinosinusitis

Background: Eosinophilic chronic rhinosinusitis (ECRS) is a subgroup of chronic rhinosinusitis with nasal polyps (CRSwNP), which is a disease characterized by eosinophilic infiltration of the sinonasal mucosa. Few studies that reported the effect of dupilumab on CRSwNP focused on a single phenotype...

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Main Authors: Daiki Nakashima, MD, Tsuguhisa Nakayama, MD, PhD, Shunsuke Minagawa, MD, PhD, Tetsuya Adachi, MD, PhD, Chieko Mitsuyama, MD, Yoko Shida, MD, Tsuneya Nakajima, MD, PhD, Shin-ichi Haruna, MD, PhD, Yoshinori Matsuwaki, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Eosinophilic chronic rhinosinusitis
dupilumab
corticosteroid
meta-analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S277282932500013X
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