Activation of Adenosine Phosphate Signaling Promotes Antitumor Immunity in Tumor Microenvironment and Facilitate Immunotherapy

Activation of Adenosine Phosphate Signaling Promotes Antitumor Immunity in Tumor Microenvironment and Facilitate Immunotherapy

ABSTRACT Adenosine 5′‐triphosphate (ATP) plays a crucial role in intracellular energetic metabolism and functions as a signal transducer in shaping the tumor microenvironment (TME). However, the understanding of the biological functions of adenosine phosphate signaling and its clinical relevance rem...

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Bibliographic Details
Main Authors: Yantao Xu, Ying Wang, Zixi Jiang, Yi He, Guowei Zhou, Benliang Wei, Jiachen Liu, Xiang Chen
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:MedComm – Oncology
Subjects:
acral melanoma
adenosine
adenosine 5′‐triphosphate (ATP)
immunotherapy
purinergic
skin cutaneous melanoma
Online Access:https://doi.org/10.1002/mog2.70022
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https://doi.org/10.1002/mog2.70022

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