Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical featuresResearch in context

Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical featuresResearch in context

Summary: Background: Ductal Carcinoma In Situ (DCIS) can progress to ipsilateral invasive breast cancer (IBC) but over 75% of DCIS lesions do not progress if untreated. Currently, DCIS that might progress to IBC cannot reliably be identified. Therefore, most patients with DCIS undergo treatment res...

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Main Authors: Shannon Doyle, Esther H. Lips, Eric Marcus, Lennart Mulder, Yat-Hee Liu, Francesco Dal Canton, Timo Kootstra, Maartje M. van Seijen, Ihssane Bouybayoune, Elinor J. Sawyer, Alastair M. Thompson, Sarah E. Pinder, Clara I. Sánchez, Jonas Teuwen, Jelle Wesseling, Jos Jonkers, Jacco van Rheenen, Marjanka Schmidt, Lodewyk F.A. Wessels, Proteeti Bhattacharjee, Alastair Thompson, Serena Nik-Zainal, Helen Davies, Andrew Futreal, Nicholas Navin, E. Shelley Hwang, Fariba Behbod, Daniel Rea, Hilary Stobart, Deborah Collyar, Donna Pinto, Ellen Verschuur, Marja van Oirsouw
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:EBioMedicine
Subjects:
Deep learning
Ductal carcinoma in situ
Multiomic integration
Risk prediction
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642500194X
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