Reporter genes and transgenic Trypanosoma cruzi (Kinetoplastida, Trypanosomatidae): applications for screening new drugs against Chagas disease

Reporter genes and transgenic Trypanosoma cruzi (Kinetoplastida, Trypanosomatidae): applications for screening new drugs against Chagas disease

Chagas disease is considered a public health issue, especially in Latin America. To this date, the course of the infection caused by the parasite Trypanosoma cruzi is yet to be completely understood and the conventional treatment do not promote a cure in the chronic phase, meaning there is an urgent...

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Main Authors: Daniele Santana de Sousa Oliveira, Elis Dionisio da Silva, Fábio Farias Galvão Júnior, Danielle Maria Nascimento Moura, Policarpo Ademar Sales-Junior, Maria Carolina Accioly Brelaz-de-Castro, Valéria Rêgo Alves Pereira
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
Subjects:
Chagas disease
Trypanosoma cruzi
transgenic parasite
reporter gene
drug screening
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1591148/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1591148/full

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