Development of a toxin-selective immunotracer for in vivo detection of Clostridioides difficile infection by immunoPET

Development of a toxin-selective immunotracer for in vivo detection of Clostridioides difficile infection by immunoPET

Abstract Background Clostridioides difficile infection (CDI) is a major healthcare challenge that is associated with high morbidity and mortality. Current diagnostic methods are limited in terms of specificity and invasiveness, necessitating novel, non-invasive imaging techniques. In this study, we...

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Main Authors: Mario González-Arjona, Lorena Cussó, Luis Alcalá, María Isabel González, Alexandra de Francisco, María Jesús Fernández-Aceñero, Dag Sehlin, Stina Syvänen, Emilio Bouza, Patricia Muñoz, Manuel Desco, Beatriz Salinas
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Clostridioides difficile
ImmunoPET
Bacterial toxin targeting
Imaging of infection
Radiotracer development
Online Access:https://doi.org/10.1186/s41181-025-00350-x
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https://doi.org/10.1186/s41181-025-00350-x

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