A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy
A 73-year-old woman was found to have a 1.7 cm axillary mass, for which a core needle biopsy was performed. The specimen revealed fragmented squamous epithelium surrounded by lymphoid tissue consistent with a squamous inclusion cyst in a lymph node, but a metastatic squamous cell carcinoma could not...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2012/418070 |
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| author | Cunxian Zhang Jinjun Xiong M. Ruhul Quddus Joyce J. Ou Katrine Hansen C. James Sung |
| author_facet | Cunxian Zhang Jinjun Xiong M. Ruhul Quddus Joyce J. Ou Katrine Hansen C. James Sung |
| author_sort | Cunxian Zhang |
| collection | DOAJ |
| description | A 73-year-old woman was found to have a 1.7 cm axillary mass, for which a core needle biopsy was performed. The specimen revealed fragmented squamous epithelium surrounded by lymphoid tissue consistent with a squamous inclusion cyst in a lymph node, but a metastatic squamous cell carcinoma could not be excluded. Within one month, the lesion enlarged to 5 cm and was excised. Touch preparation cytology during intraoperative consultation displayed numerous single and sheets of atypical epithelioid cells with enlarged nuclei and occasional mitoses, suggesting a carcinoma. However, multinucleated giant cells and neutrophils in the background indicated reactive changes. We interpreted the touch preparation as atypical and recommended conservative surgical management. Permanent sections revealed a ruptured squamous inclusion cyst in a lymph node with extensive reactive changes. Retrospectively, the atypical epithelioid cells on touch preparation corresponded to reactive histiocytes. This is the first case report of a rapidly enlarging ruptured squamous inclusion cyst in an axillary lymph node following core needle biopsy. Our case demonstrates the diagnostic challenges related to a ruptured squamous inclusion cyst and serves to inform the readers to consider this lesion in the differential diagnosis for similar situations. |
| format | Article |
| id | doaj-art-a1ce48fa2dbe450283a9db8eff489a4d |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-a1ce48fa2dbe450283a9db8eff489a4d2025-02-03T01:02:30ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/418070418070A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle BiopsyCunxian Zhang0Jinjun Xiong1M. Ruhul Quddus2Joyce J. Ou3Katrine Hansen4C. James Sung5Department of Pathology and Laboratory Medicine, Women & Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USADepartment of Pathology and Laboratory Medicine, Women & Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USADepartment of Pathology and Laboratory Medicine, Women & Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USADepartment of Pathology and Laboratory Medicine, Women & Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USADepartment of Pathology and Laboratory Medicine, Women & Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USADepartment of Pathology and Laboratory Medicine, Women & Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USAA 73-year-old woman was found to have a 1.7 cm axillary mass, for which a core needle biopsy was performed. The specimen revealed fragmented squamous epithelium surrounded by lymphoid tissue consistent with a squamous inclusion cyst in a lymph node, but a metastatic squamous cell carcinoma could not be excluded. Within one month, the lesion enlarged to 5 cm and was excised. Touch preparation cytology during intraoperative consultation displayed numerous single and sheets of atypical epithelioid cells with enlarged nuclei and occasional mitoses, suggesting a carcinoma. However, multinucleated giant cells and neutrophils in the background indicated reactive changes. We interpreted the touch preparation as atypical and recommended conservative surgical management. Permanent sections revealed a ruptured squamous inclusion cyst in a lymph node with extensive reactive changes. Retrospectively, the atypical epithelioid cells on touch preparation corresponded to reactive histiocytes. This is the first case report of a rapidly enlarging ruptured squamous inclusion cyst in an axillary lymph node following core needle biopsy. Our case demonstrates the diagnostic challenges related to a ruptured squamous inclusion cyst and serves to inform the readers to consider this lesion in the differential diagnosis for similar situations.http://dx.doi.org/10.1155/2012/418070 |
| spellingShingle | Cunxian Zhang Jinjun Xiong M. Ruhul Quddus Joyce J. Ou Katrine Hansen C. James Sung A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy Case Reports in Pathology |
| title | A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy |
| title_full | A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy |
| title_fullStr | A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy |
| title_full_unstemmed | A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy |
| title_short | A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy |
| title_sort | rapidly enlarging squamous inclusion cyst in an axillary lymph node following core needle biopsy |
| url | http://dx.doi.org/10.1155/2012/418070 |
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