Single-cell transcriptomes of dissecting the intra-tumoral heterogeneity of breast cancer microenvironment

Single-cell transcriptomes of dissecting the intra-tumoral heterogeneity of breast cancer microenvironment

Abstract Objective To investigate the mechanism by which heterogeneity in breast cancer developed and acted in single-cell transcriptomes. Methods The composition of breast cancer based on the single-cell transcriptomes of 54,055 high-quality cells from clinical specimens of 4 malignant and 4 non-ma...

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Main Authors: Peixian Chen, Kaifeng Liang, Xiaofan Mao, Qiuyuan Wu, Zhiyan Chen, Yabin Jin, Kairong Lin, Tiancheng He, Shuqing Yang, Huiqi Huang, Guolin Ye, Juntao Gao, Dan Zhou, Zhihao Zeng
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Breast cancer
Tumor heterogeneity
Single-cell RNA-Seq
EMT
Tumor associated macrophages (TAM)
Online Access:https://doi.org/10.1007/s00432-024-06015-7
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https://doi.org/10.1007/s00432-024-06015-7

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