Hydrazinyldiene-chroman-2,4-diones in inducing growth arrest and apoptosis in breast cancer cells: Synergism with doxorubicin and correlation with physicochemical properties

Hydrazinyldiene-chroman-2,4-diones in inducing growth arrest and apoptosis in breast cancer cells: Synergism with doxorubicin and correlation with physicochemical properties

This study evaluates the effects of previously synthesized hydrazinyldiene-chroman-2,4-diones on cell proliferation and apoptosis, cell cycle distribution and migration capacity of MCF-7 breast cancer cells in synergy with doxorubicin. Physicochemical properties of the synthesized compounds were cor...

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Bibliographic Details
Main Authors: Ballazhi Lulzime, Imeri Faik, Jashari Ahmed, Popovski Emil, Stojković Goran, Dimovski Aleksandar J., Mikhova Bozhana, Mladenovska Kristina
Format: Article
Language:English
Published: Sciendo 2017-03-01
Series:Acta Pharmaceutica
Subjects:
hydrazinyldiene chroman 2,4 diones
physicochemical properties
doxorubicin
cytotoxicity
breast cancer cells
Online Access:https://doi.org/10.1515/acph-2017-0006
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https://doi.org/10.1515/acph-2017-0006

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