MiRNA-mRNA network in osteoporotic fractures proposes the functional mechanism of hsa-miR-32-3p/TNFSF11 axis

MiRNA-mRNA network in osteoporotic fractures proposes the functional mechanism of hsa-miR-32-3p/TNFSF11 axis

Abstract Background and aims This study aimed to construct a miRNA-mRNA network in OF and explored the effect of the hsa-miR-32-3p/TNFSF11 axis on osteoclast function. Methods GSE70318 and GSE74209 datasets were used to filter the differentially expressed miRNAs in OF. Then, the targets of these miR...

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Bibliographic Details
Main Authors: Yukai Zeng, Bo Zhao, Jiawei Gong, Qingfeng Zhang, Fei Yang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoporotic fractures
Osteoclasts
MiRNA
TNFSF11
Hsa-miR-32-3p
Online Access:https://doi.org/10.1186/s13018-025-05836-7
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https://doi.org/10.1186/s13018-025-05836-7

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