Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome

Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome

<b>Background:</b> Hypertriglyceridemia has serious health risks such as cardiovascular disease, type 2 diabetes mellitus, nephropathy, and others. Fenofibrate is an effective hypolipidemic drug, but its benefits for ameliorating disorders associated with hypertriglyceridemia failed to b...

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Main Authors: Jan Soukop, Ludmila Kazdová, Martina Hüttl, Hana Malínská, Irena Marková, Olena Oliyarnyk, Denisa Miklánková, Soňa Gurská, Zuzana Rácová, Martin Poruba, Rostislav Večeřa
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomedicines
Subjects:
fenofibrate
silymarin
triglycerides
metabolic syndrome
oxidative stress
insulin resistance
Online Access:https://www.mdpi.com/2227-9059/13/1/212
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