Functions of Drosophila Toll/NF-κB signaling in imaginal tissue homeostasis and cancer

The Toll/NF-κB pathway plays a central role in patterning the Drosophila embryo and in orchestrating the innate immune response against microbial infections. Both discoveries were associated with a Nobel Prize award and led to the recognition of the Toll-like receptor pathway in mammals, which has s...

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Bibliographic Details
Main Authors: Fabienne Brutscher, Konrad Basler
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1559753/full
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