Single-cell RNA sequencing reveals the potential role of estrogen in tuberous sclerosis complex related renal angiomyolipoma

Abstract Purpose Tuberous sclerosis complex (TSC) is a kind of rare genetic disorder caused by TSC1/TSC2 gene mutations and presented as angiomyolipoma (AML) in kidney. Previous studies have indicated the presence of estrogen-related heterogeneity in TSC, but this aspect has not been extensively exp...

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Bibliographic Details
Main Authors: Yi Liu, Wenda Wang, Guoyang Zheng, Weifeng Xu, Zhan Wang, Xu Wang, Jiang Liu, Dongxu Qiu, Yanan Li, Yang Zhao, Yushi Zhang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-025-02909-1
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