Development and evaluation of cepharanthine-β-cyclodextrin inclusion complex oral tablets for prevention and treatment of COVID-19 lung injury

Abstract The symptoms of coronavirus disease 2019 (COVID-19) range from severe lung disease to milder manifestations, such as cough and throat irritation. As a bisbenzylisoquinoline alkaloid, cepharanthine (CEP) has various pharmacological properties, such as antifibrotic, anti-inflammatory, antioxi...

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Bibliographic Details
Main Authors: Di Liang, Zihan Lv, Zhiyun Meng, Shuchen Liu, Hui Gan, Peng Han, Zhuona Wu, Lina Du, Ruolan Gu, Guifang Dou
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-04167-1
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