Ezrin drives adaptation of monocytes to the inflamed lung microenvironment

Ezrin drives adaptation of monocytes to the inflamed lung microenvironment

Abstract Ezrin, an actin-binding protein, orchestrates the organization of the cortical cytoskeleton and plasma membrane during cell migration, adhesion, and proliferation. Its role in monocytes/macrophages (MΦs) is less understood. Here, we used a monocyte/MΦ-specific ezrin knock-out mouse model to...

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Main Authors: Ravindra Gudneppanavar, Caterina Di Pietro, Hasan H Öz, Ping-Xia Zhang, Ee-Chun Cheng, Pamela H. Huang, Toma Tebaldi, Giulia Biancon, Stephanie Halene, Adam D. Hoppe, Catherine Kim, Anjelica L. Gonzalez, Diane S. Krause, Marie E. Egan, Neetu Gupta, Thomas S. Murray, Emanuela M. Bruscia
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07255-8
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https://doi.org/10.1038/s41419-024-07255-8

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