The combination of CSF neurofilament light chain and glial fibrillary acidic protein improves the prediction of long-term confirmed disability worsening in multiple sclerosis

The combination of CSF neurofilament light chain and glial fibrillary acidic protein improves the prediction of long-term confirmed disability worsening in multiple sclerosis

Abstract Our objective was to evaluate the individual and combined prognostic attributes of baseline serum and CSF measurements of Neurofilament light chain (sNfL, cNfL) and glial fibrillary acidic protein (sGFAP, cGFAP) on long term clinical outcomes in MS. In this retrospective single center study...

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Main Authors: Simon Thebault, Seyed-Mohammad Fereshtehnejad, Hailey P Bergman, Gautier Breville, Mohammad Abdoli, Ronald A. Booth, Giulia Fadda, Mark S. Freedman, Gauruv Bose
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-75290-8
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https://doi.org/10.1038/s41598-024-75290-8

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