Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.

Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.

We describe a novel photoconversion technique to track individual cells in vivo using a commercial lipophilic membrane dye, DiR. We show that DiR exhibits a permanent fluorescence emission shift (photoconversion) after light exposure and does not reacquire the original color over time. Ratiometric i...

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Bibliographic Details
Main Authors: Alicia L Carlson, Joji Fujisaki, Juwell Wu, Judith M Runnels, Raphaël Turcotte, Joel A Spencer, Cristina Lo Celso, David T Scadden, Terry B Strom, Charles P Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0069257&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0069257&type=printable

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