Acute resistance exercise and training reduce desmin phosphorylation at serine 31 in human skeletal muscle, making the protein less prone to cleavage

Acute resistance exercise and training reduce desmin phosphorylation at serine 31 in human skeletal muscle, making the protein less prone to cleavage

Abstract Desmin intermediate filaments play a crucial role in stress transmission and mechano-protection. The loss of its integrity triggers myofibril breakdown and muscle atrophy for which desmin phosphorylation (pDes) is a priming factor. We investigated whether eccentric accentuated resistance ex...

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Bibliographic Details
Main Authors: Daniel Jacko, Kirill Schaaf, Thorben Aussieker, Lukas Masur, Jonas Zacher, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Exercise
Human skeletal muscle
Desmin
Intermediate filaments
Online Access:https://doi.org/10.1038/s41598-024-79385-0
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https://doi.org/10.1038/s41598-024-79385-0

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