Teraphtal (sodium salt of cobalt 4,5-carboxyphthalocyanine) Decreases Sensitivity of Tumor Cells to Anthracycline Antibiotics and Mitoxantrone in Vitro

Background. Anthracycline antibiotics (AA) are widely used in clinical oncohematology. As is well known АА cytotoxicity diminishes in the presence of hemin (FePPIX), an endogenous metalloporphyrine. Aim. To study effect of teraphtal (TPh) and its structural analog FePPIX on cytotoxicity of “anthr...

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Bibliographic Details
Main Authors: TA Sidorova, OO Ryabaya, VV Tatarskii, DA Khochenkov, ES Ivanova, OL Kaliya
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2018-01-01
Series:Клиническая онкогематология
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Online Access:http://bloodjournal.ru/wp-content/uploads/2018/01/2-1.pdf
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