Ritonavir loaded solid lipid nanoparticles for oral drug delivery and bioavailability enhancement

Ritonavir loaded solid lipid nanoparticles for oral drug delivery and bioavailability enhancement

Abstract Background Ritonavir is an anti-retroviral protease inhibitor to treat HIV, AIDS infections. Methods The RN-SLNs were prepared by using hot homogenization followed ultrasonication method and optimized by using a two-factor, three-level central composte design (CCD). The independent variable...

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Main Authors: Ananda Kumar Chettupalli, Sarad Pawar Naik Bukke, Shaik Abdul Rahaman, Aziz Unnisa, Madhumitha Adepu, Marati Kavitha, Molakpogu Ravindra Babu, Bayapa Reddy Narapureddy, Hope Onohuean
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Discover Applied Sciences
Subjects:
Ritonavir
Solid-lipid nanoparticles
Absorption
Bioavailability
Drug-delivery
Online Access:https://doi.org/10.1007/s42452-024-06322-1
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