miRNA-29b-1-5p mediates an antiviral activity by targeting the HBV entry receptor in human hepatocytes

miRNA-29b-1-5p mediates an antiviral activity by targeting the HBV entry receptor in human hepatocytes

Abstract Chronic hepatitis B virus (HBV) infections represent a major global health burden requiring effective therapeutic interventions. This study investigates the antiviral potential of microRNAs (miRNAs) targeting the HBV entry receptor, sodium-taurocholate cotransporting polypeptide (NTCP). Usi...

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Bibliographic Details
Main Authors: Luc Gailhouste, Yutaka Furutani, Xian-Yang Qin, Shoko Higuchi, Mariko Toguchi, Kaori Yanaka, Koichi Watashi, Takaji Wakita, Soichi Kojima
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
microRNAs
Hepatitis B virus
NTCP
RNA therapeutics
Human hepatocytes
Online Access:https://doi.org/10.1038/s41598-025-09655-y
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https://doi.org/10.1038/s41598-025-09655-y

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