Mechanistic analysis and kinetic profiling of Soai’s asymmetric autocatalysis for pyridyl and pyrimidyl substrates

Abstract Nonlinear effects in chemical reactions, coupled with amplifying catalysis, can lead to remarkable phenomena like spontaneous symmetry breaking, central to the origin of biological homochirality. Soai’s asymmetric autocatalysis is a prototypical reaction for this, where the enantiomeric exc...

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Bibliographic Details
Main Authors: Patrick Möhler, Gloria Betzenbichler, Laura Huber, Alexander F. Siegle, Oliver Trapp
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62591-3
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