Storm: Incorporating transient stochastic dynamics to infer the RNA velocity with metabolic labeling information.

The time-resolved scRNA-seq (tscRNA-seq) provides the possibility to infer physically meaningful kinetic parameters, e.g., the transcription, splicing or RNA degradation rate constants with correct magnitudes, and RNA velocities by incorporating temporal information. Previous approaches utilizing th...

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Bibliographic Details
Main Authors: Qiangwei Peng, Xiaojie Qiu, Tiejun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012606
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