Acute effects of empagliflozin on open-loop baroreflex function and urine glucose excretion in Goto-Kakizaki diabetic rats

Acute effects of empagliflozin on open-loop baroreflex function and urine glucose excretion in Goto-Kakizaki diabetic rats

Abstract Although suppression of sympathetic activity is suggested as one of the underlying mechanisms for the cardioprotective effects afforded by sodium–glucose cotransporter 2 (SGLT2) inhibitors, whether the modulation of glucose handling acutely affects sympathetic regulation of arterial pressur...

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Bibliographic Details
Main Authors: Toru Kawada, Hiromi Yamamoto, Aimi Yokoi, Akitsugu Nishiura, Midori Kakuuchi, Shohei Yokota, Hiroki Matsushita, Joe Alexander, Keita Saku
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Physiological Sciences
Subjects:
Sodium–glucose cotransporter 2
Sympathetic nerve activity
Arterial pressure
Urine flow
Equilibrium diagram
Online Access:https://doi.org/10.1186/s12576-023-00861-9
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https://doi.org/10.1186/s12576-023-00861-9

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