CD248-expressing cancer-associated fibroblasts induce epithelial–mesenchymal transition of non-small cell lung cancer via inducing M2-polarized macrophages

CD248-expressing cancer-associated fibroblasts induce epithelial–mesenchymal transition of non-small cell lung cancer via inducing M2-polarized macrophages

Abstract Non-small cell lung cancer (NSCLC)-originating cancer-associated fibroblasts (CAFs) expressing CD248 regulate interaction with immune cells to accelerate cancer progression. Epithelial–mesenchymal transition (EMT) is a key feature of metastatic cells. In our pervious study, we found that CD...

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Bibliographic Details
Main Authors: Jing Xiao, Zeyang Yang, Siyu Wang, Xinlei Liu, Yun Wang, Zuquan Hu, Zhu Zeng, Jieheng Wu
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Subjects:
CD248
Cancer-associated fibroblasts
Non-small cell lung cancer
M2 macrophages
EMT
Online Access:https://doi.org/10.1038/s41598-024-65435-0
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https://doi.org/10.1038/s41598-024-65435-0

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