Does the likelihood of malignancy in thyroid nodules with RAS mutations increase in direct proportion with the allele frequency percentage?

Does the likelihood of malignancy in thyroid nodules with RAS mutations increase in direct proportion with the allele frequency percentage?

Abstract Background Genomic testing has enhanced pre-surgical decision making for cytologically indeterminate thyroid nodules, but there remains uncertainty regarding RAS mutations. The addition of extra genetic alterations to previous driver mutation panels has been shown to improve predictive valu...

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Bibliographic Details
Main Authors: Thomas J. Hudson, Marc Philippe Pusztaszeri, Michael P. Hier, Veronique-Isabelle Forest, Ji-Wei Yang, Richard J. Payne
Format: Article
Language:English
Published: SAGE Publishing 2023-02-01
Series:Journal of Otolaryngology - Head and Neck Surgery
Subjects:
Thyroid cancer
Genetics
Cytology
Allele frequency
Thyroid nodules
Online Access:https://doi.org/10.1186/s40463-022-00611-8
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https://doi.org/10.1186/s40463-022-00611-8

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