A Novel Natural Penetration Enhancer for Transdermal Drug Delivery: In Vitro/In Vivo Evaluation and Penetration Enhancement Mechanism

A Novel Natural Penetration Enhancer for Transdermal Drug Delivery: In Vitro/In Vivo Evaluation and Penetration Enhancement Mechanism

<b>Objectives</b>: This study aimed to identify and develop a novel, safe, and effective transdermal penetration enhancer derived from the leaves of <i>Perilla frutescens</i> (L.) Britt, and to explore the underlying mechanisms of its penetration enhancement effects. <b>...

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Bibliographic Details
Main Authors: Nanxi Zhao, Jiale Hao, Yucong Zhao, Bingqian Zhao, Jiayu Lin, Jian Song, Manli Wang, Zheng Luo
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceutics
Subjects:
penetration enhancer
essential oil
perilla ketone
penetration enhancement mechanism
transdermal drug delivery
Online Access:https://www.mdpi.com/1999-4923/17/2/254
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