Essential thrombocytosis transformed AML with TP53 mutations and its clinical implications

Abstract Essential thrombocytosis (ET) is a chronic myeloproliferative neoplasm. There is a rare possibility of its transformation from ET into acute myeloid leukemia (AML). While the TP53 mutation is a well-known risk factor for AML, limited research exists regarding ET patients who develop AML wit...

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Bibliographic Details
Main Authors: Yang Si, Jiyuan Wang, Brett D Hambly, Yuli Wang, Yanfang Zhang, Shisan Bao
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-024-01665-y
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