One carbon metabolism supplementation in maturation medium but not embryo culture medium improves the yield of blastocysts from bovine oocytes

One carbon metabolism supplementation in maturation medium but not embryo culture medium improves the yield of blastocysts from bovine oocytes

Abstract Optimizing oocyte maturation and embryo culture media could enhance in vitro embryo production. The purpose of the present study was to investigate the role of supplementing one carbon metabolism (OCM) substrates and its cofactors (Cystine, Zinc, Betaine, B2, B3, B6, B12 and 5-methyltetrahy...

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Main Authors: Arefeh Golestanfar, Amir Niasari Naslaji, Farnoosh Jafarpour, Nima Sadeghi Borujen, Shiva Rouhollahi Varnosfaderani, Yves Menezo, Maurizio Dattilo, Mohammad Hossein Nasr-Esfahani
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Blastocyst rate
Cattle
One carbon metabolism
Oocyte maturation
Online Access:https://doi.org/10.1038/s41598-025-85410-7
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