Induction Therapy With Oral Tacrolimus Provides Long‐Term Benefit in Thiopurine‐Naïve Refractory Ulcerative Colitis Patients Despite Low Serum Albumin Levels

Induction Therapy With Oral Tacrolimus Provides Long‐Term Benefit in Thiopurine‐Naïve Refractory Ulcerative Colitis Patients Despite Low Serum Albumin Levels

ABSTRACT Background and Aim Oral tacrolimus is an effective treatment for refractory ulcerative colitis (UC). However, tacrolimus is underutilized because of the difficulties in transitioning to subsequent maintenance therapy and concerns about adverse events. Methods We evaluated the clinical outco...

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Main Authors: Shoko Igawa, Toshihiro Inokuchi, Sakiko Hiraoka, Junki Toyosawa, Yuki Aoyama, Yasushi Yamasaki, Hideaki Kinugasa, Masahiro Takahara, Hiroyuki Okada, Motoyuki Otsuka
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:JGH Open
Subjects:
biologics therapy
tacrolimus
thiopurine
ulcerative colitis
Online Access:https://doi.org/10.1002/jgh3.70139
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https://doi.org/10.1002/jgh3.70139

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