A novel scavenger receptor 5-based antibiotic-independent selection method for generation of stable recombinant protein-producing mammalian cell lines especially suitable for proteins affecting cell adhesion

The establishment of stable recombinant protein-producing mammalian cell lines is an expensive, time-consuming, tedious procedure. In some cases, expressed recombinant proteins have adverse effects on host cell function, including cell adhesion. Based on the adhesive properties of SCARA5, a scavenge...

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Bibliographic Details
Main Authors: Juha Risto Matias Ojala, Timo Pikkarainen, Anna Domogatskaya, Karl Tryggvason, Sergey Rodin
Format: Article
Language:English
Published: Taylor & Francis Group 2012-10-01
Series:BioTechniques
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Online Access:https://www.future-science.com/doi/10.2144/0000113936
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