Transcriptional responses to direct and indirect TGFB1 stimulation in cancerous and noncancerous mammary epithelial cells

Transcriptional responses to direct and indirect TGFB1 stimulation in cancerous and noncancerous mammary epithelial cells

Abstract Background Transforming growth factor beta (TGFβ) is important for the morphogenesis and secretory function of the mammary gland. It is one of the main activators of the epithelial–mesenchymal transition (EMT), a process important for tissue remodeling and regeneration. It also provides cel...

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Main Authors: Patryk Janus, Paweł Kuś, Roman Jaksik, Natalia Vydra, Agnieszka Toma-Jonik, Michalina Gramatyka, Monika Kurpas, Marek Kimmel, Wiesława Widłak
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Cell Communication and Signaling
Subjects:
Bystander effect
Cell death
EMT
Cell cycle
Estrogen signaling
Mammary epithelial cells
Online Access:https://doi.org/10.1186/s12964-024-01821-5
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https://doi.org/10.1186/s12964-024-01821-5

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