Challenges and strategies toward oncolytic virotherapy for leptomeningeal metastasis

Challenges and strategies toward oncolytic virotherapy for leptomeningeal metastasis

Abstract Meningeal metastasis (LM) is commonly seen in the advanced stages of cancer patients, often leading to a rapid decline in survival time and quality of life. Currently, there is still a lack of standardized treatments. Oncolytic viruses (OVs) are a class of emerging cancer therapeutics with...

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Bibliographic Details
Main Authors: Jia-Li Zhao, Bi-Lin Lin, Chen Luo, Yan-ling Yi, Peng Huang, Yu Chen, Sha Zhao, Zhen-Jie Huang, Xin-Yi Ma, Long Huang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Leptomeningeal metastasis
Oncolytic virotherapy
Intra-CSF
Oncolytic virus
Online Access:https://doi.org/10.1186/s12967-024-05794-4
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https://doi.org/10.1186/s12967-024-05794-4

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