The Influence of Vitamin C–incorporated Polycaprolactone on Osteogenesis in Osteoblast-Osteoclast Co-culture In Vitro

The Influence of Vitamin C–incorporated Polycaprolactone on Osteogenesis in Osteoblast-Osteoclast Co-culture In Vitro

ABSTRACT: Objectives: Implantation of biomaterials generates reactive oxygen species (ROS) in the peri-implant microenvironment. Bone loss occurs when ROS levels exceed the local antioxidant capacity. The aim of this study was to investigate the influence of vitamin C–incorporated polycaprolactone...

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Bibliographic Details
Main Authors: Elaf Akram Abdulhameed, K.G. Aghila Rani, Ensanya A. Abou Neel, Nadia Khalifa, Yanti Johari, Marzuki Omar, Ab Rani Samsudin
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:International Dental Journal
Subjects:
Osteoblast–osteoclast co-culture
Polycaprolactone
Vitamin C
Reactive oxygen species
Oxidative stress
Osteogenic potential
Online Access:http://www.sciencedirect.com/science/article/pii/S0020653925002369
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