Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents
1,3,4-Oxadiazoles show various biological activities and have been synthesized from different compounds. 1,3,4-oxadiazole is popularly known for its antimicrobial, anti-inflammatory, pesticidal and antihypertensive activities etc. It is well known that the synthesis of heterocyclic compounds tend to...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/698023 |
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| author | Niti Bhardwaj S. K. Saraf Pankaj Sharma Pradeep Kumar |
| author_facet | Niti Bhardwaj S. K. Saraf Pankaj Sharma Pradeep Kumar |
| author_sort | Niti Bhardwaj |
| collection | DOAJ |
| description | 1,3,4-Oxadiazoles show various biological activities and have been synthesized from different compounds. 1,3,4-oxadiazole is popularly known for its antimicrobial, anti-inflammatory, pesticidal and antihypertensive activities etc. It is well known that the synthesis of heterocyclic compounds tend to contain multi-structure in a molecule. The ring formation involves the condensation reaction. The challenge is to develop the ring system by incorporating the indole nucleus into it through the proposed reaction scheme. There are two free positions for the substitution in the oxadiazole ring system. In this study, it was planned to incorporate the oxadiazole ring system into indole ring. Synthesis of derivatives of 1,3,4-oxadiazoles from different benzaldehydes Characterization of the synthesized compounds along with their antimicrobial activity on different strains. |
| format | Article |
| id | doaj-art-a05f778e6c7b48f799d73db9c2d73d37 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-a05f778e6c7b48f799d73db9c2d73d372025-02-03T06:11:44ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-01641133113810.1155/2009/698023Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial AgentsNiti Bhardwaj0S. K. Saraf1Pankaj Sharma2Pradeep Kumar3Northern India Engineering College, Lucknow, IndiaNorthern India Engineering College, Lucknow, IndiaRaj Kumar Goel Institute of Technology, Ghaziabad, IndiaPES College of Pharmacy, Bangalore, India1,3,4-Oxadiazoles show various biological activities and have been synthesized from different compounds. 1,3,4-oxadiazole is popularly known for its antimicrobial, anti-inflammatory, pesticidal and antihypertensive activities etc. It is well known that the synthesis of heterocyclic compounds tend to contain multi-structure in a molecule. The ring formation involves the condensation reaction. The challenge is to develop the ring system by incorporating the indole nucleus into it through the proposed reaction scheme. There are two free positions for the substitution in the oxadiazole ring system. In this study, it was planned to incorporate the oxadiazole ring system into indole ring. Synthesis of derivatives of 1,3,4-oxadiazoles from different benzaldehydes Characterization of the synthesized compounds along with their antimicrobial activity on different strains.http://dx.doi.org/10.1155/2009/698023 |
| spellingShingle | Niti Bhardwaj S. K. Saraf Pankaj Sharma Pradeep Kumar Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents E-Journal of Chemistry |
| title | Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents |
| title_full | Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents |
| title_fullStr | Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents |
| title_full_unstemmed | Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents |
| title_short | Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents |
| title_sort | syntheses evaluation and characterization of some 1 3 4 oxadiazoles as antimicrobial agents |
| url | http://dx.doi.org/10.1155/2009/698023 |
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