Plant Sources, Extraction Methods, and Uses of Squalene
Squalene (SQ) is a natural compound, a precursor of various hormones in animals and sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional potential. Scientific research has shown that SQ reduces skin damage by UV radiation, LDL levels, and cholesterol in the...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Agronomy |
| Online Access: | http://dx.doi.org/10.1155/2018/1829160 |
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| author | M. Azalia Lozano-Grande Shela Gorinstein Eduardo Espitia-Rangel Gloria Dávila-Ortiz Alma Leticia Martínez-Ayala |
| author_facet | M. Azalia Lozano-Grande Shela Gorinstein Eduardo Espitia-Rangel Gloria Dávila-Ortiz Alma Leticia Martínez-Ayala |
| author_sort | M. Azalia Lozano-Grande |
| collection | DOAJ |
| description | Squalene (SQ) is a natural compound, a precursor of various hormones in animals and sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional potential. Scientific research has shown that SQ reduces skin damage by UV radiation, LDL levels, and cholesterol in the blood, prevents the suffering of cardiovascular diseases, and has antitumor and anticancer effects against ovarian, breast, lung, and colon cancer. The inclusion of SQ in the human diet is recommended without causing health risks; however, its intake is low due to the lack of natural sources of SQ and efficient extraction methods which limit its commercialization. Biotechnological advances have developed synthetic techniques to produce SQ; nevertheless, yields achieved are not sufficient for global demand for industrial or food supplement purposes. The effect on the human body is one of the scientific issues still to be addressed; few research studies have been developed with SQ from seed or vegetable sources to use it in the food sector even though squalene was discovered more than half a century ago. The aim of this review is to provide an overview of SQ to establish research focus with special reference to plant sources, extraction methods, and uses. |
| format | Article |
| id | doaj-art-a04285444816414c8c0ec560357b1d20 |
| institution | Kabale University |
| issn | 1687-8159 1687-8167 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Agronomy |
| spelling | doaj-art-a04285444816414c8c0ec560357b1d202025-02-03T06:44:31ZengWileyInternational Journal of Agronomy1687-81591687-81672018-01-01201810.1155/2018/18291601829160Plant Sources, Extraction Methods, and Uses of SqualeneM. Azalia Lozano-Grande0Shela Gorinstein1Eduardo Espitia-Rangel2Gloria Dávila-Ortiz3Alma Leticia Martínez-Ayala4Centro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, San Isidro, 62731 Yautepec, MOR, MexicoInstitute for Drug Research, School of Pharmacy, Hadassah Medical School, The Hebrew University, Jerusalem 91120, IsraelInstituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias, Campo Experimental Valle de México, Coatlinchan, 56250 Texcoco, MEX, MexicoInstituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Delegación Miguel Hidalgo, 11340 Ciudad de México, MexicoCentro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, San Isidro, 62731 Yautepec, MOR, MexicoSqualene (SQ) is a natural compound, a precursor of various hormones in animals and sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional potential. Scientific research has shown that SQ reduces skin damage by UV radiation, LDL levels, and cholesterol in the blood, prevents the suffering of cardiovascular diseases, and has antitumor and anticancer effects against ovarian, breast, lung, and colon cancer. The inclusion of SQ in the human diet is recommended without causing health risks; however, its intake is low due to the lack of natural sources of SQ and efficient extraction methods which limit its commercialization. Biotechnological advances have developed synthetic techniques to produce SQ; nevertheless, yields achieved are not sufficient for global demand for industrial or food supplement purposes. The effect on the human body is one of the scientific issues still to be addressed; few research studies have been developed with SQ from seed or vegetable sources to use it in the food sector even though squalene was discovered more than half a century ago. The aim of this review is to provide an overview of SQ to establish research focus with special reference to plant sources, extraction methods, and uses.http://dx.doi.org/10.1155/2018/1829160 |
| spellingShingle | M. Azalia Lozano-Grande Shela Gorinstein Eduardo Espitia-Rangel Gloria Dávila-Ortiz Alma Leticia Martínez-Ayala Plant Sources, Extraction Methods, and Uses of Squalene International Journal of Agronomy |
| title | Plant Sources, Extraction Methods, and Uses of Squalene |
| title_full | Plant Sources, Extraction Methods, and Uses of Squalene |
| title_fullStr | Plant Sources, Extraction Methods, and Uses of Squalene |
| title_full_unstemmed | Plant Sources, Extraction Methods, and Uses of Squalene |
| title_short | Plant Sources, Extraction Methods, and Uses of Squalene |
| title_sort | plant sources extraction methods and uses of squalene |
| url | http://dx.doi.org/10.1155/2018/1829160 |
| work_keys_str_mv | AT mazalialozanogrande plantsourcesextractionmethodsandusesofsqualene AT shelagorinstein plantsourcesextractionmethodsandusesofsqualene AT eduardoespitiarangel plantsourcesextractionmethodsandusesofsqualene AT gloriadavilaortiz plantsourcesextractionmethodsandusesofsqualene AT almaleticiamartinezayala plantsourcesextractionmethodsandusesofsqualene |