Bioinformatics analysis identifies NT5M modulates immune evasion through PD-L1 via CXCL8 in pancreatic adenocarcinoma

Bioinformatics analysis identifies NT5M modulates immune evasion through PD-L1 via CXCL8 in pancreatic adenocarcinoma

Abstract Pancreatic adenocarcinoma (PAAD) is a highly aggressive and lethal malignancy, characterized by late diagnosis, rapid progression, and poor response to conventional therapies. Altered nucleotide metabolism has recently been recognized as a critical driver of tumorigenesis, impacting cellula...

Full description

Saved in:
Bibliographic Details
Main Authors: Chaojie Zhai, Jiarong Ye, Ziyang Zhou, Hongliang Luo, Xiaoyan Li, Jipeng Liu, Xinchi Zhou, Zuao Wang, Xu Zhang, Wen Zeng, Leifeng Chen, Fan Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Pancreatic adenocarcinoma (PAAD)
NT5M
CXCL8
PD-L1
Immune
Online Access:https://doi.org/10.1038/s41598-025-10098-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-10098-8

Similar Items