Therapeutic effects of mirodenafil, a phosphodiesterase 5 inhibitor, on stroke models in rats
Mirodenafil is a phosphodiesterase 5 (PDE5) inhibitor with high specificity for its target and good blood-brain barrier permeability. The drug, which is currently used for treatment of erectile dysfunction, reduces Aβ and pTau levels and improves cognitive function in mouse models of Alzheimer'...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Neurotherapeutics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878747924001508 |
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