Characterization of a heme-degrading enzyme that mediates fitness and pathogenicity in Enterococcus faecalis

ABSTRACT Enterococcus faecalis, a gut commensal, is a leading cause of opportunistic infections. Its virulence is linked to its ability to thrive in hostile environments, which includes host-imposed metal starvation. We recently showed that E. faecalis evades iron starvation using five dedicated tra...

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Bibliographic Details
Main Authors: Debra N. Brunson, Haider Manzer, Alexander B. Smith, Joseph P. Zackular, Todd Kitten, José A. Lemos
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.00146-25
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