Divergent host humoral innate immune response to the smooth-to-rough adaptation of Mycobacterium abscessus in chronic infection

Divergent host humoral innate immune response to the smooth-to-rough adaptation of Mycobacterium abscessus in chronic infection

Mycobacterium abscessus is a nontuberculous mycobacterium emerging as a significant pathogen in individuals with chronic lung diseases, including cystic fibrosis and chronic obstructive pulmonary disease. Current therapeutics have poor efficacy. Strategies of bacterial control based on host defenses...

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Bibliographic Details
Main Authors: Emily A. Wheeler, Patricia M. Lenhart-Pendergrass, Noel M. Rysavy, Katie R. Poch, Silvia M. Caceres, Kara M. Calhoun, Karina A. Serban, Jerry A. Nick, Kenneth C. Malcolm
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cystic fibrosis
natural antibodies
complement
neutrophils
adaptation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1445660/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1445660/full

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