PARP14-mediated glycolysis enhances Tamoxifen resistance in estrogen receptor + breast cancer cells

PARP14-mediated glycolysis enhances Tamoxifen resistance in estrogen receptor + breast cancer cells

Abstract Background Resistance to Tamoxifen is a major challenge in the therapeutic management of estrogen receptor (ER) + breast cancer (BC). Glycolysis, as reported, exerts a crucial influence on the regulation of Tamoxifen resistance in BC, highlighting the need for further investigation into the...

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Bibliographic Details
Main Authors: Wenju Mo, Fanrong Zhang, Chen Wang, Xiaowen Ding, Lili Ren
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Drug resistance
ER + BC
Glycolysis
PARP14
Tamoxifen
Online Access:https://doi.org/10.1007/s12672-025-02404-7
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https://doi.org/10.1007/s12672-025-02404-7

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