Mannose receptor‐derived peptides neutralize pore‐forming toxins and reduce inflammation and development of pneumococcal disease
Abstract Cholesterol‐dependent cytolysins (CDCs) are essential virulence factors for many human pathogens like Streptococcus pneumoniae (pneumolysin, PLY), Streptococcus pyogenes (streptolysin O, SLO), and Listeria monocytogenes (Listeriolysin, LLO) and induce cytolysis and inflammation. Recently, w...
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| Main Authors: | Karthik Subramanian, Federico Iovino, Vasiliki Tsikourkitoudi, Padryk Merkl, Sultan Ahmed, Samuel B Berry, Marie‐Stephanie Aschtgen, Mattias Svensson, Peter Bergman, Georgios A Sotiriou, Birgitta Henriques‐Normark |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2020-09-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202012695 |
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